Endocrine Abstracts

A 49 yrs old lady was referred to us as her primary hypothyroidism deteriorated after exacerbation of her ulcerative colitis (UC). She also has coeliac disease. Although on levothyroxine (oral T4) 175 mcg, her thyroid stimulating hormone (TSH) remained above 40 mU/L (0.35–5.00 mU/L), and free thyroxine (FT4) was <5.15 pmol/L (9.0–20.0 pmol/L). A step wise increase of oral T4 to 900 mcg proved no benefit. Changing oral T4 tablets to syrup and addition of low dose ...